Genetics Essentials

  • HMX

Registration Deadline: January 6, 2026

Registration Deadline: February 24, 2026

Group Enrollment Option A program that is a popular choice for organizations and institutions to purchase in bulk.

Deadline Approaching Enroll now to secure your seat.

Get essential genetics knowledge to prepare for the future of health care.

  • Online; Instructor-Paced

Lessons are released weekly and remain available until the course ends.

 

Available Start Dates

January 13

March 3

$1,025

Multi-course bundle pricing is also available across enrollment periods.

Certificate

Earn a Certificate of Completion upon successfully completing all coursework.

10 Weeks, 1-2 Hours/Week

Most people can expect to spend around 15–20 hours total, but this depends on your baseline knowledge and how carefully you take notes.

  • Online; Instructor-Paced

Lessons are released weekly and remain available until the course ends.

 

Available Start Dates

January 13

March 3

$1,025

Multi-course bundle pricing is also available across enrollment periods.

Certificate

Earn a Certificate of Completion upon successfully completing all coursework.

10 Weeks, 1-2 Hours/Week

Most people can expect to spend around 15–20 hours total, but this depends on your baseline knowledge and how carefully you take notes.

On This Page

Overview

The way we diagnose and treat diseases is changing, with new technologies enabled by a deeper understanding of the human genome and its relationship to health and disease. This shift has broad implications for those who work in health care and related areas.  

During this course, you will review the essential concepts of genetics focusing on how variations in DNA sequences arise, are inherited, and can lead to disease. You will also cover the different types of studies that can be used to identify genetic variants in individuals and populations. Through an engaging, online curriculum and real-world clinical application examples, you will gain an appreciation of recent advances in the field of genetics and their potential impacts on human health and disease.  

Learning Objectives

  • Get an introduction to key concepts in genetics
  • Understand how variation in DNA sequence occurs, is inherited, and can lead to disease
  • See how advances in sequencing and genetic testing are increasing our understanding of genetic risk

Who Should Participate

Health care professionals working in roles such as R&D, product management and strategy, sales, and marketing

Overview

The way we diagnose and treat diseases is changing, with new technologies enabled by a deeper understanding of the human genome and its relationship to health and disease. This shift has broad implications for those who work in health care and related areas.  

During this course, you will review the essential concepts of genetics focusing on how variations in DNA sequences arise, are inherited, and can lead to disease. You will also cover the different types of studies that can be used to identify genetic variants in individuals and populations. Through an engaging, online curriculum and real-world clinical application examples, you will gain an appreciation of recent advances in the field of genetics and their potential impacts on human health and disease.  

Learning Objectives

  • Get an introduction to key concepts in genetics
  • Understand how variation in DNA sequence occurs, is inherited, and can lead to disease
  • See how advances in sequencing and genetic testing are increasing our understanding of genetic risk

Who Should Participate

Health care professionals working in roles such as R&D, product management and strategy, sales, and marketing

Questions?

Have questions about HMX courses, enrollment, or learning options? Contact our team by email—we’re happy to assist.

About the Course

HMX online courses bring complex material to life through engaging biomedical visualizations, clinical applications, and true-to-life scenarios paired with lectures from Harvard Medical School faculty and leading experts. 

Who Should Enroll

This advanced course is appropriate for health care professionals who are keen to enhance their understanding of the key principles of genetics and gain a broader appreciation for their clinical applications; researchers who are likely to encounter principles of genetics in their work and are seeking to enhance their expertise; professionals in managerial or health care-related roles seeking clear, easily digestible teaching on the essential principles of genetics, which will allow them to confidently engage with these concepts at a practical level.

Course Format

Most people can expect to spend around 15–20 hours total, but this depends on your baseline knowledge, how carefully you take notes, and how seriously you take the assessments. Lessons from the courses are released toward the beginning of the course session and remain available until the courses end, so you can work at your own pace. There is a final exam at the end of each course that can be taken at any time during the multi-week final exam period. The flexible course format makes this an ideal choice for working professionals.

Want to spend more time learning the foundational aspects of genetics? Consider Genetics Fundamentals instead, which will go into these topics in more depth.

Additional Course Information

For information around payments and policies, please review our frequently asked questions.

Overview of Genetics and Genomics

  • Introduction to the Genomic Revolution
  • The Human Genome

The Central Dogma and Genetic Variation

  • Representations of DNA
  • Central Dogma Overview
  • Transcription
  • Translation
  • The Central Dogma and Genetic Variation

Mendelian Inheritance of Disease

  • Meiosis and Inheritance
  • Autosomal Inheritance
  • Sex-linked Inheritance
  • Mitochondrial Inheritance
  • Pedigree Analysis
  • Penetrance and Expressivity

Genetic Variation and Architecture

  • Genetic Variation and Architecture
  • Whole Chromosome Aneuploidy
  • Structural Variation
  • Unstable Repeats
  • Common Complex Traits
  • Genetic Testing

Wrap-up

  • The Promise of Genetics in Human Health and Disease

Your progress throughout the course will determine your eligibility for a Certificate of Completion from Harvard Medical School. Earning a certificate requires significant effort; learners must complete all course material by the course end date in order to qualify.

Are you ready to elevate your educational journey and maximize the investment in your future?

You can bundle up to five courses. Bundle discounts apply to all courses selected. A bundle can consist of courses in the same upcoming enrollment period or the following enrollment period.

Two-course bundle: 25% discount 
Three-course bundle: 30% discount 
Four-course bundle: 35% discount
Five-course bundle: 40% discount

View all bundle-eligible programs. 

Limited program fee assistance is available for participants who qualify. Please email learn@hms.harvard.edu for more information.

Group Enrollments

HMX courses are ideal for organizations looking to train teams or larger groups. Group pricing is available, making it a cost-effective investment in team development.

Faculty

HMX courses are led by Harvard Medical School faculty, working in collaboration with a multi-disciplinary team of experts in biomedical visualization, assessment, and the science of learning to create a unique learning experience that will stay with you.

George Church, PhD, Robert Winthrop Professor of Genetics, Harvard Medical School / Professor of Health Sciences and Technology, Harvard Medical School

Isaac (“Zak”) Kohane, MD, PhD, Marion V. Nelson Professor of Biomedical Informatics, Harvard Medical School / Lawrence J. Henderson Professor of Pediatrics and Health Sciences and Technology, Harvard Medical School

Calum MacRae, MD, PhD, Professor of Medicine, Harvard Medical School / Cardiologist, Brigham and Women’s Hospital

Heidi Rehm, PhD, Professor of Pathology, Harvard Medical School / Chief Genomics Officer, Massachusetts General Hospital

Course Quiz

Are you ready for an advanced course? We recommend knowledge of basic chemistry, biology, and physics, as well as knowledge of key genetics concepts. Gauge your knowledge of genetics by taking this short quiz.

From Our Learners

Hear from HMX students as they share their experiences learning online with Harvard Medical School.

"If you are a student and interested in genetics, I would definitely recommend Genetics – Essentials. It starts with the basics and gradually builds on it."

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