Genetic Testing and Sequencing Technologies

  • HMX

-

Registration Deadline: August 26

Group Enrollment Option A program that is a popular choice for organizations and institutions to purchase in bulk.

Explore recent advances in genetic testing and learn about the implications for patient care.

  • Online; Instructor-Paced

Lessons are released weekly and remain available until the course ends.

$1,025

Enroll early to receive 10% off. Multi-course bundle pricing is also available. 

Early Registration Deadline:

Certificate

There are two certification levels, based on participant scores: Certificate of Achievement; Certificate of Completion

10 Weeks, 1-2 Hours/Week

Most people can expect to spend around 15–20 hours total, but this depends on your baseline knowledge and how carefully you take notes.

On This Page

Overview

The field of genetic testing is expanding and evolving at an incredible rate, due to our growing knowledge of genetic conditions, dropping costs, and higher demand. This rapid expansion has dramatically changed how we diagnose and screen for genetic conditions, who we test, and how informative the results are. Learning about the recent advances in genetic testing and sequencing technologies has important implications for anyone working in health care and related sectors. 

In this advanced HMX course, you will learn about the key developments in genetic testing and sequencing technologies, and their profound impact on health care and research sectors. Examine widely used genetic testing platforms, including traditional cytogenetics and sequencing methods (such as Sanger sequencing and sequencing by synthesis), as well as innovative technologies like DNA methylation testing and long-read sequencing. Through clear examples of the clinical applications of these technologies, such as for diagnosing and screening for genetic conditions, you will build an understanding of the strengths and limitations of each approach, as well as the clinical repercussions. Explore how further advancements could lead to enhanced, personalized health care solutions with this engaging, online course. 

Learning Objectives

  • Learn about the commonly used genetic testing platforms and their clinical applications
  • See how genetic testing is applied in clinical settings to diagnose and screen for genetic conditions
  • Get an inside look at sequencing technologies and emerging genetic tests
  • Learn how improved genetic testing can lead to better health care and precision medicine

Participant Types

Clinicians and other medical professionals; researchers in biomedicine and industry sectors; professionals in biotechnology and health care-related fields

About the Course

HMX online courses bring complex material to life through engaging biomedical visualizations, clinical applications, and true-to-life scenarios paired with lectures from Harvard Medical School faculty and leading experts. 

Who Should Apply

This advanced course is appropriate for medical professionals who are seeking to gain comprehensive insights into both recent technologies and ongoing uses of earlier technologies; researchers in biomedicine, biotechnology, or a related field who are likely to use genetic testing and/or genetic sequencing technologies in their work; professionals in managerial or sales-related roles in the clinical sector who are looking for a systematic approach to learn how genetic testing and sequencing technologies work and are used in practice.  

Course Format

Most people can expect to spend around 15–20 hours total, but this depends on your baseline knowledge, how carefully you take notes, and how seriously you take the assessments. Lessons from the courses are released toward the beginning of the course session and remain available until the courses end, so you can work at your own pace. There is a final exam at the end of each course that can be taken at any time during the multi-week final exam period. The flexible course format makes this an ideal choice for working professionals.

Additional Course Information

For information around payments and policies, please review our frequently asked questions.

Overview of Genetic Testing and Sequencing Technologies

  • What is Genetic Testing?
  • The Promise of Genetic Testing and Sequencing Technologies

Clinical Genetic Testing

  • Overview of Genetic Testing
  • Traditional Cytogenetics
  • Microarray Diagnostics
  • Biochemical Genetic Tests
  • Diagnostic Genetic Testing
  • Reproductive Genetic Testing
  • Predictive Genetic Testing
  • Clinical Linkage: Prenatal Genetic Testing

Sequencing Technologies

  • Sequencing Approaches
  • Polymerase Chain Reaction
  • Sanger Sequencing
  • Sequencing by Synthesis
  • Raw Data Analysis
  • Variant Identification and Classification
  • Variant Reporting Errors
  • Clinical Linkage: Diagnostic Genetic Testing

Emerging Areas in Genetic Testing and Analysis

  • Non-coding Variants
  • DNA Methylation Testing
  • Improving Variant Classification
  • Complex Trait Variants
  • Determining Risk in Complex Traits
  • Long Read Sequencing
  • Single Cell Sequencing
  • Progress Towards Patient Customized Healthcare
  • Clinical Linkage: Variant Classification and the EpiChroma Clinic

Wrap-up

  • The Future of Genetic Testing and Sequencing Technologies

We recommend knowledge of basic chemistry, biology, and physics, as well as knowledge of key genetics concepts. This is an advanced course; for those who require more background in genetics, we offer Genetics: Essentials

Your scores and participation in assessments throughout the course, including a final exam, will determine whether you qualify for a Certificate of Achievement or Certificate of Completion from Harvard Medical School. Earning a certificate requires significant effort, and not all participants will meet that level of achievement. You will not receive a letter grade (A, B, C, and so on). 

Are you ready to elevate your educational journey and maximize the investment in your future?

You can bundle up to five courses. Bundle discounts apply to all courses selected. All courses in a bundle must be completed during the following two enrollment periods.

Two-course bundle: 25% discount 
Three-course bundle: 30% discount 
Four-course bundle: 35% discount
Five-course bundle: 40% discount

View all bundle-eligible programs. 

Group Enrollments

HMX courses are ideal for organizations looking to train teams or larger groups. Group pricing is available, making it a cost-effective investment in team development.

Faculty

HMX courses are led by Harvard Medical School faculty, working in collaboration with a multi-disciplinary team of experts in biomedical visualization, assessment, and the science of learning to create a unique learning experience that will stay with you.

Mark Daly, PhD, Associate Professor of Medicine, Harvard Medical School / Geneticist, Massachusetts General Hospital

Christine DeGennaro, PhD, Lecturer in Genetics, Harvard Medical School (former)

Amit Khera, MD, MSc, Assistant Professor of Medicine, Harvard Medical School / Cardiologist, Massachusetts General Hospital

Cynthia Morton, PhD, Professor of Pathology, Harvard Medical School / Medical Geneticist, Brigham and Women’s Hospital

Anne O’Donnell Luria, MD, PhD, Instructor in Pediatrics, Harvard Medical School / Medical Geneticist, Boston Children’s Hospital

Michelle Pacione, EdM, MS, LCGC, Genetic Counselor, Brigham and Women’s Hospital

Timothy Yu, MD, PhD, Associate Professor of Pediatrics, Harvard Medical School / Neurologist, Boston Children’s Hospital

Course Quiz

Are you ready for an advanced course? We recommend knowledge of basic chemistry, biology, and physics, as well as knowledge of key genetics concepts. Gauge your knowledge of pharmacology by taking this short quiz.

From Our Learners

Hear from HMX students as they share their experiences learning online with Harvard Medical School.

"I particularly liked the clinical linkage section of every module, which delved into real-life applications and cases about the material given. This helped better contextualize the theoretical concepts I learned through benefits delivered to patients."

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