Dana-Farber Center for BRCA & Related Genes Scientific Symposium

  • Continuing Education
BRCA GENE.

Registration Deadline: November 11

Explore the latest advances in hereditary cancer research and care at the Dana-Farber Center for BRCA and Related Genes Scientific Symposium, designed for clinicians and researchers to deepen knowledge of detection, treatment, and ethical issues in BRCA-associated cancers across multiple tumor types.

  • In Person

This course requires in person attendance.

This is the standard price, for a full list of profession pricing see below.
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Continuing Education Credits

Earn up to:
6.75 AMA PRA Category 1 Credit(s) ™
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One Day

Please view the Schedule for a full description of the program.

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Overview

Dana-Farber Cancer Institute Center for BRCA and Related Genes Scientific Symposium is for clinicians, researchers, and anyone interested in learning more about BRCA 1/2 and related genes and exploring the latest research in a variety of cancer types affected by the mutations in the BRCA pathway.

Learning Objectives

  • Identify current and emerging approaches to early detection, screening, and prevention of hereditary breast, ovarian, pancreatic, and prostate cancers associated with mutations in the BRCA pathway.
  • Recognize and analyze the latest clinical and translational discoveries in the treatment of breast, ovarian, pancreatic, and prostate cancers associated with hereditary or acquired mutations in BRCA1/2 and related genes.
  • Discuss current ethical, legal, social as well as diversity and inclusion issues related to carriers of BRCA1/2 and related genes.

Developed and Offered By:

  • Dana-Farber Cancer Institute Center for BRCA & Related Genes Logo

Continuing Education courses are developed by faculty from Harvard Medical School's teaching hospitals and accredited by Harvard Medical School. This course is offered by Dana-Farber Cancer Institute.

Participant Types

Specialty Physicians, Researchers, Clinicians, and Others

Schedule

All agenda sessions are in Eastern Time.

Day 1

Tuesday, November 11, 2025

Registration and Opening Remarks

Panos Konstantinopoulos

8:00-8:30 am

Systemic therapy in homologous recombination deficient breast cancer

Susan Domchek; Alan D'Andrea

8:30-9:30 am

Aging as a Common Path to Breast Cancer Risk

Alan D'Andrea; Mark Labarge

9:30-10:15 am

Break

10:15-10:30 am

Ovarian cancer and early drug development

Stephanie Lheureux

10:30-11:15 am

Tuvusertib (ATRi)-based combinations to overcome PARP inhibitor resistance: early clinical experience

Alan D'Andrea; Ioannis Gounaris

11:15 am-12:00 pm

Lunch

12:00-1:00 pm

Rational DDR inhibitor combinations with immunotherapy and ADCs

Geoffrey Shapiro; Panos Konstantinopoulos

1:00-1:45 pm

Breast cancer in young BRCA carriers: The experience of the BRCA BCY collaboration

Geoffrey Shapiro; Matteo Lambertini

1:45-2:30 pm

PARP-inhibitor resistance – Beyond reversion mutations

Gerburg Wulf

2:30-3:15 pm

Break

3:15-3:30 pm

Nucleotide excision repair (NER) deficiency as a synthetic lethal target in solid tumors

Kent Mouw; Geoffrey Shapiro

3:30-4:15 pm

DNA damage and repair

Geoffrey Shapiro; Gaorav Gupta

4:15-5:00 pm

Closing Remarks

Panos Konstantinopoulos

5:00-5:15 pm

Faculty

Harvard Medical School Continuing Education attracts the best and brightest faculty from all around the world. As a student in this course, you’ll have access to outstanding course directors and faculty.

Brittany Bychkovsky, MD, MSc
Assistant Professor of Medicine, Harvard Medical School

Susan Domchek, MD
Director, Cancer Risk Evaluation Program, Abramson Cancer Center, University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania
Executive Director, Basser Center for BRCA

Ioannis Gounaris, MD, PhD
VP, Head of Clinical Development DNA Damage Response (DDR), Merck

Gaorav Gupta, MD, PhD
Assistant Professor of Radiation Oncology, University of North Carolina Chapel Hill

Mark Labarge, PhD
Professor
Department of Population Sciences
Director, Postdoctoral Training Program
Deputy Director, Center for Cancer and Aging
Beckman Research Institute at City of Hope

Matteo Lambertini, MD, PhD
Associate Professor, University of Genova

Stephanie Lheureux, MD, PhD
Clinician Investigator, Princess Margaret Cancer Centre
Cancer Clinical Research Unit (CCRU), Princess Margaret Cancer Centre

Kent Mouw, MD, PhD
Assistant Professor of Radiation Oncology, Harvard Medical School
Co-Director, Bladder Cancer Center

Geoffrey Shapiro, MD, PhD
Senior Vice President, Developmental Therapeutics, Dana-Farber Cancer Institute

Gerburg Wulf, MD
Associate Professor, Medicine, Harvard Medical School
Active Staff, Hematology/Oncology, Beth Israel Deaconess Medical Center

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Course Fees

Fee Disclaimer

You may register through our secure online environment and will receive an email confirmation upon receipt of your payment.

Review the cancellation policy.

Role Standard Price
Physician (MD/DO) Free
Nurse (RN/APRN) Free
Psychologist Free
Resident/Fellow Free
Social Worker Free
Allied Health Professional / Other Free

Accreditation

In support of improving patient care, Harvard Medical School is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The Harvard Medical School designates this live activity for a maximum of 6.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For the purpose of recertification, the American Academy of Nurse Practitioners Certification Board and American Nurses Credentialing Center accept AMA PRA Category 1 Credit™ issued by organizations accredited by the ACCME (Accreditation Council for Continuing Medical Education). We would also suggest that learners check with their state licensing board to ensure they accept reciprocity with AMA PRA Category 1 Credit™ for re-licensure. 

The National Commission on Certification of Physician Assistants (NCCPA) states that AMA PRA Category 1 Credits™ are acceptable for continuing medical education requirements for recertification. We would also suggest that learners check with their state licensing board to ensure they accept reciprocity with AMA PRA Category 1 Credit™ for re-licensure.

The American Medical Association (AMA) has an agreement of mutual recognition of continuing medical education (CME) credit with the European Union of Medical Specialties (UEMS). Additional information regarding this agreement may be found on the European Union of Medical Specialties website.

The Royal College of Physicians and Surgeons of Canada recognizes conferences and workshops held outside of Canada that are developed by a university, academy, hospital, specialty society or college as accredited group learning activities.

Competencies

This course is designed to meet the following Institute of Medicine Core Competencies:

  • Provide Patient-Centered Care
  • Work in Interdisciplinary Teams
  • Employ Evidence-Based Practice
  • Apply Quality Improvement
  • Utilize Informatics

This course is designed to meet the following American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Educational (ACGME) competencies:

  • Medical Knowledge
  • Professionalism
  • Systems-Based Practice
  • Interpersonal and Communication Skills

Dislcaimer & Disclosure

CME activities accredited by Harvard Medical School are offered solely for educational purposes and do not constitute any form of certification of competency. Practitioners should always consult additional sources of information and exercise their best professional judgment before making clinical decisions of any kind.

Note: AMA PRA Category 1 Credit™ is calculated based on submission of a preliminary agenda and may be subject to change.

In accord with the disclosure policy of the Medical School as well as standards set forth by the Accreditation Council for Continuing Medical Education (ACCME), course planners, speakers, and content reviewers have been asked to disclose any relationships they have to companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. In addition, faculty have been asked to list any off-label uses of pharmaceuticals and/or devices for investigational or non-FDA approved purposes that they plan to discuss.

Registration for courses managed by Harvard Medical School can only be completed through Harvard Medical School’s official registration portal: cmeregistration.hms.harvard.edu. Attendee registrations made through any other sites cannot be honored and will not be refunded. Please report any unauthorized websites or solicitations for registrations.

Program Specialties