Biochemistry Fundamentals

  • HMX
Cell org drawing from Biochemistry course

Registration Deadline: April 7

Registration Deadline: June 2

Deadline Approaching Enroll now to secure your seat.

Group Enrollment Option A program that is a popular choice for organizations and institutions to purchase in bulk.

Learn why human health is dependent on chemistry, and what that means for clinical care.

  • Online; Instructor-Paced

Lessons from the courses are released weekly and remain available until the courses end, so you can work at your own pace.

 

Available Start Dates

April 14

June 9

$1,025

Multi-course bundle pricing is also available across enrollment periods. The student price for an individual course is $800 and cannot be combined with course discounts.

Certificate

Earn a Certificate of Completion upon successfully completing all coursework.

10 Weeks, 4-6 Hours/Week

Most people can expect to spend around 40-60 hours total, but this depends on your baseline knowledge and how carefully you take notes.

  • Online; Instructor-Paced

Lessons from the courses are released weekly and remain available until the courses end, so you can work at your own pace.

 

Available Start Dates

April 14

June 9

$1,025

Multi-course bundle pricing is also available across enrollment periods. The student price for an individual course is $800 and cannot be combined with course discounts.

Certificate

Earn a Certificate of Completion upon successfully completing all coursework.

10 Weeks, 4-6 Hours/Week

Most people can expect to spend around 40-60 hours total, but this depends on your baseline knowledge and how carefully you take notes.

On This Page

Overview

Understanding biochemistry is an excellent foundation for learning all of biology, but it can be difficult to make sense of the complexity of biochemical systems. 

In this foundational course, you will learn about the principles governing the interactions of individual molecules, and how those same principles apply at the scale of cells and organisms. Along the way, you will see how biochemistry intersects with human disease and clinical care. Engaging, interactive lessons will help you gain an in-depth understanding of biochemistry and equip you for future work in health care and related sectors. 

Learning Objectives

  • Understand fundamental principles of energy and thermodynamics, and the importance of enzymes in biochemical pathways
  • Learn about cellular specialization and how cell functions are explained by the chemical properties and structure of biological molecules
  • See how foundational concepts apply in real-life scenarios and clinical settings

Who Should Participate

Pre-med students; Current medical students; Health care professionals working in R&D, product management and strategy, sales, and marketing

Overview

Understanding biochemistry is an excellent foundation for learning all of biology, but it can be difficult to make sense of the complexity of biochemical systems. 

In this foundational course, you will learn about the principles governing the interactions of individual molecules, and how those same principles apply at the scale of cells and organisms. Along the way, you will see how biochemistry intersects with human disease and clinical care. Engaging, interactive lessons will help you gain an in-depth understanding of biochemistry and equip you for future work in health care and related sectors. 

Learning Objectives

  • Understand fundamental principles of energy and thermodynamics, and the importance of enzymes in biochemical pathways
  • Learn about cellular specialization and how cell functions are explained by the chemical properties and structure of biological molecules
  • See how foundational concepts apply in real-life scenarios and clinical settings

Who Should Participate

Pre-med students; Current medical students; Health care professionals working in R&D, product management and strategy, sales, and marketing

Questions?

Have questions about HMX courses, enrollment, or learning options? Contact our team by email—we’re happy to assist.

About the Course

HMX online courses bring complex material to life through engaging biomedical visualizations, clinical applications, and true-to-life scenarios paired with lectures from Harvard Medical School faculty and leading experts. 

Who Should Enroll

This foundational course is appropriate for pre-med and current medical students interested in building their foundational knowledge of medical science, as well as professionals in health care and related fields who need a fundamental understanding of biochemistry – including those working in R&D, product management, strategy, sales, marketing, and other roles. 

Course Format

Most people can expect to spend around 40-60 hours total, but this depends on your baseline knowledge, how carefully you take notes, and how seriously you take the assessments. Lessons from the courses are released weekly and remain available until the courses end, so you can work at your own pace. The course wraps up with a final exam administered the final two days of the session.

Additional Course Information

Course Overview 

  • Course introduction
  • Meet the faculty

The Rules of Energy

  • Thermodynamics of chemical reactions
  • Equilibrium and Le Chatelier’s principle
  • The role of enzymes and enzyme regulation
  • Glycolysis

How Energy is Harnessed

  • Coupling chemical reactions
  • Energy currencies: ATP and NADH
  • The tricarboxylic acid cycle
  • The electron transport chain

How Energy is Transformed

  • Bypass reactions and catabolic pathways
  • Gluconeogenesis
  • Metabolic networks
  • Diet and energy

Cellular Specialization

  • Cellular metabolic specialization
  • The liver and muscle in carbohydrate metabolism
  • The role of adipose tissue in lipid metabolism
  • Diabetes

Compartmentalization of Biochemical Pathways

  • Membranes and organelles
  • Pumps and osmolarity
  • Sequestration of chemical reactions
  • Fatty acid synthesis and oxidation
  • The secretory pathway

Signaling Pathways

  • Response to stimuli
  • Receptors, ligands, and enzyme cascades
  • Positive and negative feedback
  • Endocrine signaling (insulin and glucagon)

The Chemistry of Life

  • The hydrophobic effect
  • Amino acid and protein structure
  • How structure dictates function
  • Inhibitors
  • Allosteric and covalent enzyme regulation

Frequently Asked Questions

Follow the link below for more information around payment and policies.

Biochemistry Fundamentals introduces the chemical principles that underlie how cells and organisms function. You’ll learn about energy and thermodynamics, enzymes and metabolic pathways, cellular specialization, signaling, and how biochemical processes relate to human disease and clinical care.  

Highlights include clear explanations of complex biochemical pathways, interactive visualizations, and real clinical scenarios that show how biochemistry informs diagnosis and treatment. The course emphasizes metabolism, compartmentalization, and signaling, helping you build a strong foundation for future medical and biomedical study. 

This foundational course is ideal for premed and current medical students, as well as health care and life science professionals in R&D, product management, strategy, sales, and marketing who need a rigorous yet accessible introduction to biochemistry,.

This course is a good fit if you want a medically oriented introduction to biochemistry that connects directly to human health and disease. It works well if you’re preparing for or currently in health professions training, transitioning into the life sciences or biopharma industry, or need to strengthen your biochemistry background for exams, graduate study, or work with clinical and R&D teams.

Learners commonly include pre-med and medical students, residents, nurses, physician assistants, research coordinators, and professionals from pharma, biotech, and medical device companies. Many participants have a mix of undergraduate science coursework and early-career experience in health care, life sciences, or related business roles.

You will gain a stronger command of core biochemical principles that underlie physiology, pharmacology, and disease mechanisms. This foundation can make future coursework easier, improve your readiness for standardized exams, and help you communicate more effectively with clinicians, researchers, and technical stakeholders—adding credibility to your CV or professional profile with a Certificate of Completion from Harvard Medical School. 

Expertise in biochemistry typically involves an undergraduate degree in a life science field plus advanced training such as medical school, a PhD, or a master’s program in biochemistry or related disciplines, along with research or clinical experience. Biochemistry Fundamentals does not replace a degree, but it gives you a medically focused, clinically relevant foundation that can support success in those more advanced programs or in biopharma and health care roles. 

Biochemistry Fundamentals is a 10 week, online, instructor-paced course, with an estimated time commitment of 4–6 hours per week (about 40–60 hours total).

Your progress throughout the course will determine your eligibility for a Certificate of Completion from Harvard Medical School. Earning a certificate requires significant effort; learners must complete all course material by the course end date in order to qualify.

You can bundle up to five courses. Bundle discounts apply to all courses selected. A bundle can consist of courses in the same upcoming enrollment period or the following enrollment period.

Two-course bundle: 25% discount 
Three-course bundle: 30% discount 
Four-course bundle: 35% discount
Five-course bundle: 40% discount

View all bundle-eligible programs.

The student price for an individual course is $800. The student pricing discount is only available for foundational HMX courses and cannot be combined with course bundles

Limited program fee assistance is available for participants who qualify. Please email learn@hms.harvard.edu for more information.

Group Enrollments

HMX courses are ideal for organizations looking to train teams or larger groups. Group pricing is available, making it a cost-effective investment in team development.

Faculty

HMX courses are led by Harvard Medical School faculty, working in collaboration with a multi-disciplinary team of experts in biomedical visualization, assessment, and the science of learning to create a unique learning experience that will stay with you.

Marie E. McDonnell, MD, Lecturer on Medicine, Harvard Medical School / Endocrinologist, Brigham and Women’s Hospital

Eli Miloslavsky, MD, Assistant Professor of Medicine, Harvard Medical School / Rheumatologist, Massachusetts General Hospital

HMX Faculty Perspectives

Why do you think it’s important for health care professionals to learn biochemistry?

"To be able to provide effective medical care to patients, health care professionals need to first understand how the human body functions in health and in disease. To truly gain this understanding, you need to master what happens at the smallest functional units of the body – the cells and the molecules within them – and how these small units aggregate into a functional human body. In a way, biochemistry is the core of medicine; health care providers rely on an understanding of biochemistry in most of their routine tasks."  -Ole-Petter (“OP”) Hamnvik, MB BCh BAO, MMSc

View More HMX Faculty Perspectives

From Our Learners

Hear from HMX students as they share their experiences learning online with Harvard Medical School.

"[This course] would be very helpful for students who are struggling with the concepts in class, mainly because the strength of the HMX program is that it explains difficult concepts in more easily understandable language."

Explore Related Programs

Bundle courses together for discounted pricing.

Physiology Fundamentals

Build a body of knowledge on the systems that keep bodies functioning.

  • HMX Online Learning
  • Online; Instructor-Paced
  • Registration Deadline Approaching:
  • Group Enrollment Option

Dates: -

For: Pre-med students; Current medical students; Health care professionals working in R&D, product management and strategy, sales, and marketing

Immunology Fundamentals

Get an in-depth look at how the body fights disease – and how new therapies can help.

  • HMX Online Learning
  • Online; Instructor-Paced
  • Registration Deadline Approaching:
  • Group Enrollment Option

Dates: -

For: Pre-med students; Current medical students; Health care professionals working in R&D, product management and strategy, sales, and marketing

Pharmacology Fundamentals

Get an in-depth look at how drugs and other therapeutics can be used to treat and prevent diseases.

  • HMX Online Learning
  • Online; Instructor-Paced
  • Registration Deadline Approaching:
  • Group Enrollment Option

Dates: -

For: Pre-med students; Current medical students; Health care professionals working in R&D, product management and strategy, sales, and marketing

Genetics Fundamentals

Learn about the building blocks of life – and the future of medicine.

  • HMX Online Learning
  • Online; Instructor-Paced
  • Registration Deadline Approaching:
  • Group Enrollment Option

Dates: -

For: Pre-med students; Current medical students; Health care professionals working in R&D, product management and strategy, sales, and marketing

Request Information

Interested in learning more about this program? Sign up for details.

CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

In order to comply with applicable U.S. export control and sanctions regulations, Harvard Medical School prohibits access to and use of Harvard Medical School educational offerings, programs and resources to individuals from certain sanctioned regions or who are otherwise subject to U.S. government sanctions, unless appropriate authorization is in place.

In order to comply with applicable U.S. export control and sanctions regulations, Harvard Medical School prohibits access to and use of Harvard Medical School educational offerings, programs and resources to individuals from certain sanctioned regions or who are otherwise subject to U.S. government sanctions, unless appropriate authorization is in place.

Program Topics