Internal Medicine Comprehensive Review and Update 2026
- Continuing Education
This program, the 66th annual Internal Medicine Comprehensive Review and Update from the leading clinical faculty of Harvard Medical School and Massachusetts General Hospital, provides comprehensive, high-yield instruction to ensure clinicians are current with the latest evidence and best practices to optimize patient care.
- Live Online
This program uses state-of-the-art streaming technology to present sessions online in real time. Participants can attend from any location, and can interact with faculty via live chat.
Additionally, all sessions will be recorded and made available to participants for online viewing for 6 months after the end of the course--through December 30, 2026.
All live streaming and recorded sessions are eligible for AMA PRA Category 1 Credits™ and other relevant credits, up to the approved maximum. (Note: Evaluations must be completed within 30 days in order to receive CME credit.)
$1,495
This is the full tuition for physicians. A $100 early registration discount is available.
For tuition for other medical professionals, please see the full table below.
Early Registration Deadline:
Continuing Education Credits
Earn up to:
» 60.00 AMA PRA Category 1 Credits™
» 60.00 ABIM MOC points
» 60:00 AAFP Live Prescribed credits
» 60.00 ECME Credits®
6 Days
This 6-day intensive program, which is among the highest-rated Harvard Medical School CME courses, updates busy clinicians on evidence-based best practices in internal medicine.
On This Page
Overview
Comprehensive Updates, Strategies, and Practice Recommendations for State-of-the-Art Internal Medicine
Internal Medicine Comprehensive Review and Update 2026 is a live online course, using live streaming, electronic Q&A, and other remote learning technologies.
This program, the 66th annual Internal Medicine Comprehensive Review and Update from the leading clinical faculty of Harvard Medical School and Massachusetts General Hospital, provides comprehensive, high-yield instruction to ensure clinicians are current with the latest evidence and best practices to optimize patient care.
This program covers the breadth of Internal Medicine subspecialties, including:
- Cardiovascular Medicine
- Hematology and Oncology, including CAR T-cell therapies
- Immunotherapies and Biologics
- Pulmonary and Critical Care Medicine
- Infectious Diseases
- Gastroenterology
- Endocrinology
- Rheumatology
- Nephrology
- Obesity Medicine
- Women’s Health
- Geriatrics
- Hospital Medicine
- Allergy and Immunology
- Neurology
- Psychiatry
- Palliative Care
- Pain Medicine
Practical, Results-Focused Education for Ambulatory and Inpatient Settings
Enhance your skills and optimize your patient outcomes by joining Harvard Medical School’s most distinguished faculty—across all relevant fields of Internal Medicine—as they provide updates, best practices, and clinical strategies designed to improve day-to-day practice in both ambulatory and inpatient settings.
In addition to being live streamed, all sessions will be recorded and placed in the online course library, enabling registrants to view them at their convenience. Recordings will be available for viewing for 6 months after the conclusion of the course--through December 30, 2026. All live streaming and recorded sessions are eligible for AMA PRA Category 1 Credits™ and other relevant credits, up to the approved maximum. (Note: Evaluations must be completed within 30 days in order to receive CME credit.)
Developed and Offered By:
Continuing Education courses are developed by faculty from Harvard Medical School's teaching hospitals and accredited by Harvard Medical School. This course is offered by Massachusetts General Hospital.
Participant Types
- Internists
- Family Physicians
- Medical Specialists
- Nurse Practitioners
- Physician Assistants
- ...and other medical professionals who want a comprehensive review of Internal Medicine and its subspecialties.
Schedule
This program is among the highest-rated Harvard Medical School CME courses.
All schedule times are Eastern Daylight Time.
Please note that program changes / substitutions may be made without notice.
Monday, June 1, 2026
Introduction
7:00-7:15 am
Acute Kidney Injury: A Practical Framework
7:15-8:00 am
Venous Thromboembolic Disease: A Practical Approach
8:00-9:00 am
Giant Cell Arteritis and Polymyalgia Rheumatica: Novel Approaches
9:00-9:45 am
9:45-10:15 am
Fever Syndromes in 2026 (Noninfectious)
10:15-11:00 am
Dysnatremias: A Practical Approach
11:00 am-12:00 pm
The Use of Opioids for Chronic Pain Management
12:00-12:45 pm
12:45-1:15 pm
Systemic Lupus for the Clinician
1:15-1:45 pm
Update in Management of Chronic Kidney Disease, Including ESRD
1:45-2:30 pm
Demistifying Laboratory Interpretation in Rheumatology
2:30-3:00 pm
Inflammatory Arthritis Syndromes: What's New
3:00-3:30 pm
Hot Topics in Critical Care Nephrology
3:30-4:15 pm
4:15-4:30 pm
Metabolic Health in 2026
4:30 pm - 7:15 pm
Fatty Liver Disease: Key Concepts in Management
4:30-5:15 pm
Pharmacologic Management of Obesity in 2026
5:15-6:00 pm
Exercise for Health: What's New in 2026
6:00-6:45 pm
Q&A
6:45-7:15 pm
Addiction Medicine
4:30 pm - 7:15 pm
Update in Opiate Use Disorder in in Clinical Practice
4:30-5:15 pm
Infections in Patients with Opiate Use Disorder
5:15-6:00 pm
Alcohol Use Disorder
6:00-6:45 pm
Q&A
6:45-7:15 pm
Tuesday, June 2, 2026
Q & A with the Professors
7:00-7:30 am
Contemporary Diagnosis and Management of Hypertensive Disorders
7:30-8:15 am
Sepsis Update in 2026
8:15-9:00 am
Type 2 Diabetes: A Comprehensive Review for the Practicing Clinician
9:00-9:45 am
9:45-10:00 am
Osteoporosis: A Practical Approach for 2026
10:00-10:45 am
New Frontiers in Tobacco Cessation 2026
10:45-11:30 am
Contemporary Management Strategies in Diabetes 2026
11:30 am-12:15 pm
Menopause in 2026: What to Know
12:15-12:45 pm
12:45-1:30 pm
Hospital Medicine Update
1:30-2:15 pm
Allergy and Immunology Update
2:15-3:00 pm
What's New in Sleep Apnea
3:00-3:30 pm
Anemia and Other Hematology Cases: Interactive Session
3:30-4:15 pm
4:15-4:30 pm
Asthma Diagnosis and Management in 2026
4:30-5:15 pm
Chronic Cough: How to Approach and How to Manage
5:15-6:00 pm
COPD in 2026
6:00-6:45 pm
Update on Ovarian and Cervical Cancer Screening: What's New in 2026
6:45-7:30 pm
Wednesday, June 3, 2026
Q & A with the Professors
7:00-7:30 am
HIV/AIDS Update in 2026
7:30-8:15 am
COVID-19 in 2026: Lessons Learned and Key Management Strategies
8:15-9:00 am
Urinary Tract Infections: A Contemporary Approach to Diagnosis and Management
9:00-9:45 am
C. diff Update: Latest Concepts
9:45-10:30 am
10:30-10:45 am
Cases in Critical Care Medicine in 2026
10:45-11:15 am
Thyroid Disorders in 2026
11:15 am-12:00 pm
Pneumonia: A Practical Approach in 2026
12:00-12:45 pm
CPC New England Journal of Medicine
12:45-1:45 pm
1:45-2:30 pm
Skin/Soft Tissue Infections for the Clinician
2:30-3:15 pm
What's New in Immunizations for the Practicing Clinician: Navigating the Maze
3:15-4:00 pm
4:00-4:15 pm
Common ENT and Respiratory Infections in Clinical Practice: What's New
4:15-5:00 pm
Infections in the Immunocompromised Host
5:00-5:30 pm
Antibiotics: What You Need to Know in 2026
5:30-6:15 pm
Update in Sexually Transmitted Diseases
6:15-7:15 pm
Thursday, June 4, 2026
Q & A with the Professors
7:00-7:30 am
Breast Cancer Screening and Prevention in 2026
7:30-8:15 am
Breast Cancer Management: What's New in the Field
8:15-9:00 am
Coagulation I
9:00-9:45 am
9:45-10:00 am
Coagulation II
10:00-10:45 am
What You Need to Know About Immunotherapies in Oncology
10:45-11:30 am
The Evolution of Obesity Care 2026
11:30 am-12:30 pm
12:30-1:15 pm
Colon Cancer Screening Update in 2026
1:15-2:00 pm
Update in Prostate Cancer
2:00-2:30 pm
Viral Hepatitis
2:30-3:15 pm
Update in Gastroesophageal Reflux Disease and Irritable Bowel Syndrome
3:15-4:00 pm
Update in GI Malignancies in 2026
4:00-4:45 pm
4:45-5:00 pm
New Frontiers in Hem/Onc 2026
5:00 pm - 7:45 pm
Car-T Cell Therapy for the Clinician: Nuts and Bolts
5:00-5:45 pm
New Frontiers in Rapid Cancer Screening in 2026
5:45-6:30 pm
Lifestyle and Cancer
6:30-7:15 pm
Q&A
7:15-7:45 pm
Key Advances in Cardiology in 2026
5:00 pm - 7:45 pm
Nutrition and Cardiac Disease: What the Clinician Needs to Know
5:00-5:45 pm
New Frontiers in Cardio-Oncology
5:45-6:30 pm
Hot Topics in Valvular Disease, Including Infective Endocarditis
6:30-7:15 pm
Q&A
7:15-7:45 pm
Friday, June 5, 2026
Q & A with the Professors
7:00-7:30 am
Best Approaches in the Evaluation of Patients with CAD
7:30-8:15 am
Atrial Fibrillation and Ventricular Arrhythmias in 2026
8:15-9:00 am
Acute Coronary Syndrome in 2026
9:00-9:45 am
9:45-10:00 am
Contemporary Approach to Heart Failure Management
10:00-10:45 am
Thoracic Aorta Disease Update
10:45-11:15 am
AI in Medicine: A New Frontier
11:15 am-12:00 pm
12:00-12:30 pm
Q & A Session with Cardiology
12:30-1:15 pm
Hyperlipidemia: Latest Concepts
1:15-2:00 pm
Medical Management of CAD: What's New
2:00-2:45 pm
Lung Cancer Update
2:45-3:30 pm
Delirium in 2026: What the Clinician Needs to Know
3:30-4:00 pm
4:00-4:15 pm
TB Update in 2026
4:15-4:45 pm
Contemporary Management in Cirrhosis
4:45-5:30 pm
Peripheral Arterial Disease: What You Need to Know
5:30-6:00 pm
Palliative Care Update
6:00-7:00 pm
Saturday, June 6, 2026
Headaches and Stroke: Update for the Clinician
7:00-8:00 am
Cases in Geriatrics: Pearls for the Practicing Clinician
8:00-8:45 am
Update on Depression and Anxiety in 2026
8:45-9:45 am
9:45 am-10:15 am
New Frontiers in Dementia: Updates and Clinical Pearls
10:15-11:15 am
Heart Disease in Women in 2026
11:15 am-12:00 pm
2026 Program Highlights
Highlights of the 2026 program, comprising 80+ high-impact, incisive educational sessions, include:
- Comprehensive updates across all areas of Internal Medicine presented by Harvard Medical School’s leading clinical faculty and most distinguished teachers
- Specific evidence-based recommendations to incorporate updates into practice for optimized patient care and outcomes
- AI in health care
- Outcomes-driven strategies to improve diagnosis and management of diseases seen in both ambulatory and inpatient settings
- Case-based sessions and daily Q&A sessions with Harvard faculty
- New in 2026: Workshops spanning advances in Cardiology, Hematology-Oncology, Addiction Medicine, and Metabolic Health
- Expanded treatment options for:
- Cardiovascular disease (including CVD in women and preventive Cardiology)
- Obesity (including novel medical therapies and lifestyle management)
- Diabetes and novel therapeutic strategies
- Women’s health
- COPD, asthma, and obstructive sleep apnea
- Smoking cessation
- GERD, functional bowel disorders, and upper tract diseases
- Vasculitis, SLE, rheumatoid arthritis, and more
- Cirrhosis and metabolic dysfunction-associated steatotic liver disease (MASLD)
- The state of the art in:
- Coronary artery disease screening
- Acute coronary syndrome management
- Anticoagulation strategies
- Management of obesity and metabolic health
- Lifestyle and cancer
- Delirium and dementia and updated management strategies
- Thromboembolic disease and its complications
- Immunotherapies in Hematology-Oncology
- Cancer screening strategies (including novel rapid diagnostics)
- Contemporary management of pneumonia
- HIV medicine, care of the immunosuppressed host, and skin/soft tissue infections
- Management of C. difficile (including new therapies)
- Immunization strategies and updates
- Diagnostic and treatment strategies for viral hepatitis
- Acute kidney injury and care of patients with chronic kidney disease
- Management of urinary tract infections—new 2025 guidelines
- Osteoporosis management and approach to the patient with menopausal symptoms
- Diagnosis and management of anxiety and depression
- The latest guidelines for:
- Breast cancer, ovarian cancer, prostate cancer, and colon cancer screening
- Hyperlipidemia and hypertension
- Diagnosis and management of sepsis
- UTI management
- Rational antibiotic use in the era of rising antimicrobial resistance
- A live, interactive New England Journal of Medicine (NEJM) Clinicopathologic Conference (CPC) session
- Metabolic Health in 2026
- Addiction Medicine
- New Frontiers in Hematology-Oncology
- Key Advances in Cardiology in 2026
Practice-Changing Education
Past participants report that this course has inspired and changed their practice.
CLICK HERE to hear how.
Optimized for Remote Education
The 2026 program has been enhanced for distance learning:
- Live streamed sessions
- Q&A with the Professors
- Recordings of all live streamed education made available to participants for online viewing, at your convenience, through December 30, 2026.
- Easy access to these recordings will permit those in different time zones or who have scheduling conflicts to avoid missing out on any sessions that are important to them.
- In addition, participants can review sessions previously watched via live stream to reinforce key learning points.
- All live streaming and recorded sessions are eligible for AMA PRA Category 1 Credits™ and other relevant credits, up to the approved maximum. (Note: Evaluations must be completed within 30 days in order to receive CME credit.)
Learning Objectives
Upon completion of this course, participants will be able to:
- Apply the most up-to-date and evidence-based recommendations for diagnosis and clinical management of the most relevant illnesses seen across Internal Medicine.
- Incorporate new clinical and translational research findings across Internal Medicine and its subspecialties into more effective approaches in medical management across a wide array of clinical settings (ambulatory and inpatient).
- Identify the full the breadth and depth of diagnostic and management strategies used in everyday clinical practice as guided by the medical literature with the aim to improve patient outcomes.
Faculty
Course Directors
Rocío Hurtado
MD, DTM&H
- Assistant Professor of Medicine, Harvard Medical School
- Director of Mycobacterial Center of Excellence, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital
Jose C. Florez
MD, PhD
- Physician-in-Chief and Chair, Department of Medicine;
- Investigator, Center for Genomic Medicine, Massachusetts General Hospital
- Institute Member, Broad Institute
- Professor of Medicine, Harvard Medical School
2026 faculty list coming soon.
2026 faculty list coming soon.
Course Fees
Fee Disclaimer
Registrations for Harvard Medical School CME programs are made via our secure online registration system. At the end of the registration process, a $10 non-refundable processing fee will be added to your registration.
Upon receipt of your paid registration, an email confirmation will be sent to you. Be sure to include an email address that you check frequently. Your email address is used for critical information, including registration confirmation, evaluation, and certificate.
Please review the cancellation policy.
Early Registration Deadline:
| Role | Course Fee | Early Registration Course Fee |
|---|---|---|
| Physician (MD/DO) | $1,495.00 | $1,395.00 |
| Nurse (RN/APRN) | $1,395.00 | $1,295.00 |
| PA | $1,395.00 | $1,295.00 |
| Resident/Fellow | $1,395.00 | $1,295.00 |
| Allied Health Professional / Other | $1,395.00 | $1,295.00 |
All registrants of Internal Medicine Comprehensive Review and Update will receive an electronic syllabus.
All sessions will be recorded as they are live streamed and placed in the online course video library, so that registrants can review them at their convenience. The video library will be available through December 30, 2026.
Accreditation
The Harvard Medical School designates this live activity for a maximum of 60.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 60.00 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points.
The AAFP has reviewed Internal Medicine Comprehensive Review and Update 2026 and deemed it acceptable for up to 60.00 Live AAFP Prescribed credit(s). Term of Approval is from 06/01/2026 to 06/06/2026. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This activity meets the criteria of the Massachusetts Board of Registration in Medicine for 6.00 credits of Risk Management Study. This includes:
- 2.00 credits of Opioid Education and Pain Management Training
- 1.75 credits of End-of-Life Care Education
Please check your individual state licensing board requirements before claiming these credits.
For the purpose of recertification, the American Academy of Nurse Practitioners Certification Board and American Nurses Credentialing Center accept AMA PRA Category 1 Credit™ issued by organizations accredited by the ACCME (Accreditation Council for Continuing Medical Education). We would also suggest that learners check with their state licensing board to ensure they accept reciprocity with AMA PRA Category 1 Credit™ for re-licensure.
The National Commission on Certification of Physician Assistants (NCCPA) states that AMA PRA Category 1 Credits™ are acceptable for continuing medical education requirements for recertification. We would also suggest that learners check with their state licensing board to ensure they accept reciprocity with AMA PRA Category 1 Credit™ for re-licensure.
The American Medical Association (AMA) has an agreement of mutual recognition of continuing medical education (CME) credit with the European Union of Medical Specialties (UEMS). Additional information regarding this agreement may be found on the European Union of Medical Specialties website.
The Royal College of Physicians and Surgeons of Canada recognizes conferences and workshops held outside of Canada that are developed by a university, academy, hospital, specialty society or college as accredited group learning activities.