Internal Medicine
Comprehensive Review and Update 2026
- Continuing Education
This comprehensive review, delivered by the leading clinical faculty of Harvard Medical School and Massachusetts General Hospital, ensures clinicians are current with best practices and the latest guidelines across Internal Medicine. Participants sharpen their diagnostic and treatment skills to improve patient care in both ambulatory and inpatient settings.
- Live Online
This program uses state-of-the-art streaming technology to present sessions online in real time. Participants can attend from any location, and can interact with faculty via live chat.
Additionally, all sessions will be recorded and made available to participants for online viewing for 6 months after the end of the course.
All live streaming and recorded sessions and workshops are eligible for AMA PRA Category 1 Credits™ and other relevant credits, up to the approved maximum. (Note: Evaluations must be completed within 30 days in order to receive CME credit.)
$1,395 Save with early registration
Save $100. The tuition listed above is for physicians; see the course fee table for pricing for other health professionals. To ensure your participation at the lowest possible cost, early registration is strongly recommended.
Fee increases to $1,495 after
Continuing Education
Earn up to:
» 65.50 AMA PRA Category 1 Credits™
» 65.50 ABIM MOC points
» 60.00 AAFP Live Prescribed credits
» 65.50 ECME Credits®
6 Days
This intensive program, which is among the highest-rated Harvard Medical School CME courses, updates busy clinicians on evidence-based best practices in internal medicine.
On This Page
Overview
Comprehensive Updates, Strategies, and Practice Recommendations for State-of-the-Art Internal Medicine
Internal Medicine Comprehensive Review and Update 2026 is a live online course, using live streaming, electronic Q&A, and other remote learning technologies optimized for interaction with faculty.
This 66th annual review and update from the leading clinical faculty of Harvard Medical School and Massachusetts General Hospital provides comprehensive, high-yield instruction to ensure clinicians are current with the latest evidence and best practices to optimize patient care.
This program covers the breadth of Internal Medicine, including:
- Cardiovascular Medicine
- Hematology and Oncology, including CAR T-cell therapies
- Immunotherapies and Biologics
- Pulmonary and Critical Care Medicine
- Infectious Diseases
- Gastroenterology
- Endocrinology
- Rheumatology
- Obesity Medicine
- Nephrology
- Women’s Health
- Hospital Medicine
- Allergy and Immunology
- Neurology
- Psychiatry
- Addiction Medicine
- Palliative Care
- Geriatrics
- Pain Medicine
Practical, Results-Focused Education for Ambulatory and Inpatient Settings
Enhance your skills and optimize your patient outcomes with updates, best practices, and clinical strategies that improve day-to-day practice in both ambulatory and inpatient settings.
In addition to being live streamed, all sessions will be recorded and placed in the online course library, enabling registrants to view them at their convenience. Recordings will be available for viewing for 6 months after the conclusion of the course. All live streaming and recorded sessions and workshops are eligible for AMA PRA Category 1 Credits™ and other relevant credits, up to the approved maximum. (Note: Evaluations must be completed within 30 days in order to receive CME credit.)
Developed and Offered By:
Continuing Education courses are developed by faculty from Harvard Medical School's teaching hospitals and accredited by Harvard Medical School. This course is offered by Massachusetts General Hospital.
Who Should Participate
- Internists
- Family Physicians
- Medical Specialists
- Nurse Practitioners
- Physician Assistants
- Pharmacists
... and other medical professionals who want a comprehensive review of Internal Medicine and its subspecialties.
Course Directors
Rocío Hurtado, MD, DTM&H
Director of the Mycobacterial Center of Excellence
Infectious Disease Division
Department of Medicine, Massachusetts General Hospital
Assistant Professor of Medicine, Harvard Medical School
Andrew S. Allegretti, MD, MSc
Director of Critical Care Nephrology
Nephrology Division
Department of Medicine, Massachusetts General Hospital
Associate Professor of Medicine, Harvard Medical School
Jose C. Florez, MD, PhD
Physician-in-Chief and Chair, Department of Medicine, Mass General Brigham
Investigator, Center for Genomic Medicine, Massachusetts General Hospital
Institute Member, Broad Institute
Jackson Professor of Clinical Medicine, Harvard Medical School
Schedule
This program is among the highest-rated Harvard Medical School CME courses.
All schedule times are Eastern Daylight Time.
Please note that program changes / substitutions may be made without notice.
Monday, June 1, 2026
Introduction
Drs. Rocío Hurtado, Andrew Allegretti, and Jose Florez
7:00-7:15 am
Acute Kidney Injury: A Practical Framework
Dr. Andrew Lundquist
7:15-8:00 am
Venous Thromboembolic Disease: A Practical Approach
Dr. Samuel Goldhaber
8:00-9:00 am
Giant Cell Arteritis and Polymyalgia Rheumatica: Novel Approaches
Dr. Sebastian Unizony
9:00-9:45 am
9:45-10:15 am
Recurrent Fever Syndromes in Adults
Dr. Jonathan Hausmann
10:15-11:00 am
Dysnatremias: A Practical Approach
Dr. Juan Carlos Ayus
11:00 am-12:00 pm
The Use of Opioids for Chronic Pain Management
Dr. Gary Brenner
12:00-12:45 pm
12:45-1:15 pm
Systemic Lupus for the Clinician
Dr. Karen Costenbader
1:15-1:45 pm
Update in Management of Chronic Kidney Disease, Including ESRD
Dr. David Steele
1:45-2:30 pm
Demystifying Laboratory Interpretation in Rheumatology
Dr. Sara Schoenfeld
2:30-3:00 pm
Inflammatory Arthritis Syndromes: What's New
Dr. Sheila Arvikar
3:00-3:30 pm
Hot Topics in Critical Care Nephrology
Dr. Andrew Allegretti
3:30-4:15 pm
4:15-4:30 pm
Metabolic Health in 2026
Monday Workshop Option A
4:30 - 7:15 pm
Fatty Liver Disease: Key Concepts in Management
Dr. Kathleen Corey
4:30-5:15 pm
Pharmacologic Management of Obesity in 2026
Dr. Caroline Apovian
5:15-6:00 pm
Exercise for Health: What's New in 2026
Dr. Meagan Wasfy
6:00-6:45 pm
Q&A
6:45-7:15 pm
Addiction Medicine
Monday Workshop Option B
4:30 - 7:15 pm
Update in Opiate Use Disorder in in Clinical Practice
Dr. Sarah Wakeman
4:30-5:15 pm
Infections in Patients with Opiate Use Disorder
Dr. Daniel Solomon
5:15-6:00 pm
Alcohol Use Disorder
Dr. Gene Lambert
6:00-6:45 pm
Q&A
6:45-7:15 pm
Tuesday, June 2, 2026
Q & A with the Professors
7:00-7:30 am
Contemporary Diagnosis and Management of Hypertensive Disorders
Dr. Randall Zusman
7:30-8:15 am
Sepsis Update in 2026
Dr. Eric Schmidt
8:15-9:00 am
Type 2 Diabetes: A Comprehensive Review for the Practicing Clinician
Dr. David Nathan
9:00-9:45 am
9:45-10:00 am
Osteoporosis: A Practical Approach for 2026
Dr. Elaine Yu
10:00-10:45 am
New Frontiers in Tobacco Cessation 2026
Dr. Nancy Rigotti
10:45-11:30 am
Contemporary Management Strategies in Diabetes 2026
Dr. Deborah Wexler
11:30 am-12:15 pm
Menopause in 2026: What to Know
Dr. Mahmooda Qureshi
12:15-12:45 pm
12:45-1:30 pm
Hospital Medicine Update
Dr. Melissa Mattison
1:30-2:15 pm
Allergy and Immunology Update
Dr. Aleena Banerji
2:15-3:00 pm
What's New in Sleep Apnea
Dr. James Mojica
3:00-3:30 pm
Anemia and Other Hematology Cases: Interactive Session
Dr. David Sykes
3:30-4:15 pm
4:15-4:30 pm
Asthma Diagnosis and Management in 2026
Dr. Rod Rahimi
4:30-5:15 pm
Chronic Cough: How to Approach and How to Manage
Dr. Kai Saukkonen
5:15-6:00 pm
COPD in 2026
Dr. Walter O'Donnell
6:00-6:45 pm
Update on Ovarian and Cervical Cancer Screening: What's New in 2026
Dr. Marcela del Carmen
6:45-7:30 pm
Wednesday, June 3, 2026
Q & A with the Professors
7:00-7:30 am
HIV/AIDS Update in 2026
Dr. Rajesh Gandhi
7:30-8:15 am
COVID-19 in 2026: Lessons Learned and Key Management Strategies
Dr. Arthur Kim
8:15-9:00 am
Urinary Tract Infections: A Contemporary Approach to Diagnosis and Management
Dr. Jacob Lazarus
9:00-9:45 am
C. diff Update: Latest Concepts
Dr. Jessica Allegretti
9:45-10:30 am
10:30-10:45 am
Cases in Critical Care Medicine in 2026
Dr. Kathryn Hibbert
10:45-11:15 am
Thyroid Disorders in 2026
11:15 am-12:00 pm
Pneumonia: A Practical Approach in 2026
Dr. Joshua Metlay
12:00-12:45 pm
New England Journal of Medicine (NEJM) Clinicopathologic Conference
Dr. Eric Rosenberg
12:45-1:45 pm
1:45-2:30 pm
Skin/Soft Tissue Infections for the Clinician
Dr. Sandra Nelson
2:30-3:15 pm
What's New in Immunizations for the Practicing Clinician: Navigating the Maze
Dr. Edward Ryan
3:15-4:00 pm
4:00-4:15 pm
Common ENT and Respiratory Infections in Clinical Practice: What's New
Dr. Miriam Barshak
4:15-5:00 pm
Infections in the Immunocompromised Host
Dr. Camille Kotton
5:00-5:30 pm
Antibiotics: What You Need to Know in 2026
Dr. Alyssa Letourneau
5:30-6:15 pm
Update in Sexually Transmitted Diseases
Dr. Donna Felsenstein
6:15-7:15 pm
Thursday, June 4, 2026
Q & A with the Professors
7:00-7:30 am
Breast Cancer Screening and Prevention in 2026
Dr. Wendy Chen
7:30-8:15 am
Breast Cancer Management: What's New in the Field
Dr. Irene Kuter
8:15-9:00 am
Coagulation I
Dr. David Kuter
9:00-9:45 am
9:45-10:00 am
Coagulation II
Dr. David Kuter
10:00-10:45 am
What You Need to Know About Immunotherapies in Oncology
Dr. Kerry Reynolds
10:45-11:30 am
The Evolution of Obesity Care 2026
Dr. Lee Kaplan
11:30 am-12:30 pm
12:30-1:15 pm
Colon Cancer Screening Update in 2026
Dr. Daniel Chung
1:15-2:00 pm
Update in Prostate Cancer
Dr. Anthony D'Amico
2:00-2:30 pm
Viral Hepatitis
Dr. Raymond Chung
2:30-3:15 pm
Update in Gastroesophageal Reflux Disease and Irritable Bowel Syndrome
Dr. Kyle Staller
3:15-4:00 pm
Update in GI Malignancies in 2026
Dr. David Ryan
4:00-4:45 pm
4:45-5:00 pm
New Frontiers in Hem/Onc 2026
Thursday Workshop Option A
5:00 - 7:45 pm
Car-T Cell Therapy for the Clinician: Nuts and Bolts
5:00-5:45 pm
New Frontiers in Rapid Cancer Screening in 2026
Dr. Douglas Micalizzi
5:45-6:30 pm
Lifestyle and Cancer
Dr. Amy Comander
6:30-7:15 pm
Q&A
7:15-7:45 pm
Key Advances in Cardiology in 2026
Thursday Workshop Option B
5:00 - 7:45 pm
Nutrition and Cardiac Disease: What the Clinician Needs to Know
Dr. Robert Ostfeld
5:00-5:45 pm
New Frontiers in Cardio-Oncology
Dr. Tomas Neilan
5:45-6:30 pm
Hot Topics in Valvular Disease, Including Infective Endocarditis
Dr. Evin Yucel
6:30-7:15 pm
Q&A
7:15-7:45 pm
Friday, June 5, 2026
Q & A with the Professors
7:00-7:30 am
Best Approaches in the Evaluation of Patients with CAD
7:30-8:15 am
Medical Management of CAD: What's New
Dr. Farouc Jaffer
8:15-9:00 am
Acute Coronary Syndrome in 2026
Dr. Marc Sabatine
9:00-9:45 am
9:45-10:00 am
Atrial Fibrillation and Ventricular Arrhythmias in 2026
Dr. Moussa Mansour
10:00-10:45 am
Thoracic Aorta Disease Update
Dr. Eric Isselbacher
10:45-11:15 am
TB Update in 2026
Dr. Rocío Hurtado
11:15 am-12:00 pm
12:00-12:30 pm
Q & A Session with Cardiology
12:30-1:15 pm
Hyperlipidemia: Latest Concepts
Dr. Pradeep Natarajan
1:15-2:00 pm
Contemporary Approach to Heart Failure Management
Dr. Christopher Newton-Cheh
2:00-2:45 pm
Lung Cancer Update
Dr. Ibiayi Dagogo-Jack
2:45-3:30 pm
Delirium in 2026: What the Clinician Needs to Know
Dr. Felicia Smith
3:30-4:00 pm
4:00-4:15 pm
AI in Medicine: A New Frontier
4:15-4:45 pm
Contemporary Management in Cirrhosis
4:45-5:30 pm
Peripheral Arterial Disease: What You Need to Know
Dr. Douglas Drachman
5:30-6:00 pm
Palliative Care Update
Dr. Bethany-Rose Daubman
6:00-7:00 pm
Saturday, June 6, 2026
Headaches and Stroke: Update for the Clinician
Dr. Aneesh Singhal
7:00-8:00 am
Cases in Geriatrics: Pearls for the Practicing Clinician
Dr. Fadi Ramadan
8:00-8:45 am
Update on Depression and Anxiety in 2026
Dr. Guy Maytal
8:45-9:45 am
9:45 am-10:15 am
New Frontiers in Dementia: Updates and Clinical Pearls
Dr. Mark Albers
10:15-11:15 am
Heart Disease in Women in 2026
Dr. Amy Sarma
11:15 am-12:00 pm
Program Highlights
The 2026 program includes:
- 90+ high-impact, incisive educational sessions
- Outcomes-driven strategies to improve diagnosis and management of diseases seen in both ambulatory and inpatient settings
- Case-based sessions and daily Q&A sessions with the faculty
- Workshops spanning advances in Cardiology, Hematology-Oncology, Addiction Medicine, and Metabolic Health
- New topics: AI in Medicine, Noninfectious Fever Syndromes, Hepatorenal Syndromes, and many more
- Specific evidence-based recommendations to incorporate updates into practice for optimized patient care
Expanded treatment options for:
- Cardiovascular disease (including CVD in women and preventive Cardiology)
- Obesity (including novel medical therapies and lifestyle management)
- Diabetes and novel therapeutic strategies
- Women’s health
- COPD, asthma, and obstructive sleep apnea
- Smoking cessation
- GERD, functional bowel disorders, and upper tract diseases
- Vasculitis, SLE, rheumatoid arthritis, and more
- Cirrhosis and metabolic dysfunction-associated steatotic liver disease (MASLD)
The state of the art in:
- Coronary artery disease screening
- Acute coronary syndrome management
- AI in medicine
- Anticoagulation strategies
- Management of obesity and metabolic health
- Lifestyle and cancer
- Delirium and dementia and updated management strategies
- Thromboembolic disease and its complications
- Immunotherapies in Hematology-Oncology
- Cancer screening strategies (including novel rapid diagnostics)
- Contemporary management of pneumonia
- HIV medicine, care of the immunosuppressed host, and skin/soft tissue infections
- Management of C. difficile (including new therapies)
- Immunization strategies and updates
- Diagnostic and treatment strategies for viral hepatitis
- Acute kidney injury and care of patients with chronic kidney disease
- Management of urinary tract infections—the newest guidelines
- Osteoporosis management and approach to the patient with menopausal symptoms
- Diagnosis and management of anxiety and depression
The latest guidelines for:
- Breast cancer, ovarian cancer, prostate cancer, and colon cancer screening
- Hyperlipidemia and hypertension
- Diagnosis and management of sepsis
- UTI management
- Rational antibiotic use in the era of rising antimicrobial resistance
A live, interactive New England Journal of Medicine (NEJM) Clinicopathologic Conference (CPC) session
Metabolic Health in 2026
- Fatty Liver Disease: Key Concepts in Management
- Pharmacologic Management of Obesity in 2026
- Exercise for Health: What's New in 2026
Addiction Medicine
- Update in Opiate Use Disorder in Clinical Practice
- Infections in Patients with Opiate Use Disorder
- Alcohol Use Disorder
New Frontiers in Hematology-Oncology
- Car-T Cell Therapy for the Clinician: Nuts & Bolts
- New Frontiers in Rapid Cancer Screening in 2026
- Lifestyle and Cancer
Key Advances in Cardiology in 2026
- Nutrition and Cardiac Disease: What the Clinician Needs to Know
- New Frontiers in Cardio-Oncology
- Hot Topics in Valvular Disease including Infective Endocarditis
Past participants report that this course has inspired and changed their practice. CLICK HERE to hear how.
Optimized for Remote Education
The 2026 program has been enhanced for distance learning:
- Live streamed sessions
- Q&A with the faculty
- Recordings of all live streamed education made available to participants for online viewing, at your convenience, through December 30, 2026.
- Easy access to these recordings will permit those in different time zones or who have scheduling conflicts to avoid missing out on any sessions that are important to them.
- In addition, participants can review sessions previously watched via live stream to reinforce key learning points.
- All live streaming and recorded sessions and workshops are eligible for AMA PRA Category 1 Credits™ and other relevant credits, up to the approved maximum. (Note: Evaluations must be completed within 30 days in order to receive CME credit.)
Learning Objectives
Upon completion of this course, participants will be able to:
- Apply the most up-to-date and evidence-based recommendations for diagnosis and clinical management of the most relevant illnesses seen across Internal Medicine.
- Incorporate new clinical and translational research findings across Internal Medicine and its subspecialties into more effective approaches in medical management across a wide array of clinical settings (ambulatory and inpatient).
- Identify the full the breadth and depth of diagnostic and management strategies used in everyday clinical practice as guided by the medical literature with the aim to improve patient outcomes.
Faculty
Course Directors
Rocío Hurtado
MD, DTM&H
- Director of the Mycobacterial Center of Excellence
- Infectious Disease Division
- Department of Medicine, Massachusetts General Hospital
- Assistant Professor of Medicine, Harvard Medical School
Andrew S. Allegretti
MD, MSc
- Director of Critical Care Nephrology
- Nephrology Division
- Department of Medicine, Massachusetts General Hospital
- Associate Professor of Medicine, Harvard Medical School
Jose C. Florez
MD, PhD
- Physician-in-Chief and Chair, Department of Medicine, Mass General Brigham
- Investigator, Center for Genomic Medicine, Massachusetts General Hospital
- Institute Member, Broad Institute
- Jackson Professor of Clinical Medicine, Harvard Medical School
2026 faculty list coming soon.
2026 faculty list coming soon.
Course Fees
Fee Disclaimer
Registrations for Harvard Medical School CME programs are made via our secure online registration system. At the end of the registration process, a $10 non-refundable processing fee will be added to your registration.
Upon receipt of your paid registration, an email confirmation will be sent to you. Be sure to include an email address that you check frequently. Your email address is used for critical information, including registration confirmation, evaluation, and certificate.
Please review the cancellation policy.
Early Registration Deadline:
| Role | Course Fee | Early Registration Course Fee |
|---|---|---|
| Physician (MD/DO) | $1,495.00 | $1,395.00 |
| Nurse (RN/APRN) | $1,395.00 | $1,295.00 |
| PA | $1,395.00 | $1,295.00 |
| Resident/Fellow | $1,395.00 | $1,295.00 |
| Allied Health Professional / Other | $1,395.00 | $1,295.00 |
All registrants of Internal Medicine Comprehensive Review and Update will receive an electronic syllabus.
All sessions will be recorded as they are live streamed and placed in the online course video library, so that registrants can review them at their convenience. The video library will be available through December 30, 2026.
Accreditation
The Harvard Medical School designates this live activity for a maximum of 65.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 65.50 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points.
The AAFP has reviewed Internal Medicine Comprehensive Review and Update 2026 and deemed it acceptable for up to 60.00 Live AAFP Prescribed credit(s). Term of Approval is from 06/01/2026 to 06/06/2026. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This activity meets the criteria of the Massachusetts Board of Registration in Medicine for 6.00 credits of Risk Management Study. This includes:
- 2.00 credits of Opioid Education and Pain Management Training
- 1.75 credits of End-of-Life Care Education
Please check your individual state licensing board requirements before claiming these credits.
For the purpose of recertification, the American Academy of Nurse Practitioners Certification Board and American Nurses Credentialing Center accept AMA PRA Category 1 Credit™ issued by organizations accredited by the ACCME (Accreditation Council for Continuing Medical Education). We would also suggest that learners check with their state licensing board to ensure they accept reciprocity with AMA PRA Category 1 Credit™ for re-licensure.
The National Commission on Certification of Physician Assistants (NCCPA) states that AMA PRA Category 1 Credits™ are acceptable for continuing medical education requirements for recertification. We would also suggest that learners check with their state licensing board to ensure they accept reciprocity with AMA PRA Category 1 Credit™ for re-licensure.
The American Medical Association (AMA) has an agreement of mutual recognition of continuing medical education (CME) credit with the European Union of Medical Specialties (UEMS). Additional information regarding this agreement may be found on the European Union of Medical Specialties website.
The Royal College of Physicians and Surgeons of Canada recognizes conferences and workshops held outside of Canada that are developed by a university, academy, hospital, specialty society or college as accredited group learning activities.