Skin Inflammation in Human Health and Disease
- Continuing Education

Unlock new insights into skin immunity and therapeutic innovation in this dynamic course, where top researchers and clinicians present cutting-edge discoveries and practical strategies for advancing the treatment of inflammatory skin diseases.
- In Person
This course requires in person attendance.
Fairmont Copley Plaza, Boston, MA
On This Page
Overview
This course will focus on skin and its role in human health and disease. The speakers will present the most recent findings that better our understanding the role of human skin as a barrier, immunologic organ, and readily accessible avenue for drug delivery. Cutting edge research techniques and strategies will be discussed that can be applied by investigative dermatologists looking to develop new directions in research. Research findings that can be applied to clinical practice will be discussed and emphasized. By the end of this conference, participants will have an improved understanding of the complex relationship between the immune system and the skin.
The course will begin on Wednesday, June 25, at 7:00pm with a two-hour poster session. Entrants will be chosen in advance based upon abstracts submitted prior to the conference. The bulk of the conference will be held on Thursday and Friday. Topics that will be covered will include: The role of the innate and adaptive immune system in skin immunity, Skin as a barrier, Interplay between the skin and microbiome, Emerging therapeutics in Skin Disease, and Emerging Technologies for human skin disease research. Information will be presented in lecture format with a brief period for questions and answers following each presentation. Speakers are a diverse group of leading faculty from regional, national, and international institutions who will provide a broad field of discourse on both the basic science and clinical implications of the most recent research in cutaneous immunology.
Learning Objectives
- Summarize the recent advances in inflammatory skin diseases which will help physicians achieve better outcomes.
- Recognize appropriate management and treatment options for inflammatory skin diseases and utilize these approaches in routine clinical practice.
- Clarify the basic biology of inflammatory skin disease so that participants will be able to select evidence-based treatment regimens and apply recent clinical evidence to selection of treatment for different inflammatory skin diseases.
- Communicate the biology of skin disorders so that participants will be able to more effectively convey the biology of the disease to patients, enhancing understanding and treatment compliance.
Developed and Offered By:
Continuing Education courses are developed by faculty from Harvard Medical School's teaching hospitals and accredited by Harvard Medical School. This course is offered by Brigham and Women's Hospital.
Schedule
All agenda sessions are in Eastern Time.
Wednesday, June 25, 2025
Registration
5:00-7:00 pm
Poster Presentation Session and Reception - CME credits not available for this session
7:00-9:00 pm
Thursday, June 26, 2025
Breakfast
7:30-8:00 am
Welcome
Rachael Clark
8:00-8:15 am
Fortification and Repair of the Multi-Faceted Skin Barrier via Microbiota-Host Interactions
Elizabeth Grice
8:15-8:45 am
Antimicrobial Peptides & Human Disease
RIchard Gallo
8:45-9:15 am
Translating Cytokine Signaling: Lessons Learned and Future Opportunities
John O'Shea
9:15-9:45 am
Break - Poster Session
9:45-10:15 am
Innate Mechanisms of Skin Inflammation
Michel Gilliet
10:15-10:45 am
Mechanisms and Motifs of Itch in the Skin and Beyond
Brian Kim
10:45-11:15 am
Granzyme K Drives a New Pathway of Complement Activation that Contributes to Inflammatory Skin Disease Pathology
Erin Theisen
11:15-11:30 am
Using AlphaFold-Multimer for Discovery of Nanobody Antagonists to the Itch Receptor MRGPRX2
Jeffrey Smith
11:30-11:45 am
ARID5B Controls Pathologic Iflammatory Versus Invasive Fibroblast Behavior
Angela Zou
11:45 am-12:00 pm
Lunch
12:00-1:00 pm
Regulation of T Cell Activation in Human Skin by CD1 and Lipids
Annemieke de Jong
1:00-1:30 pm
The Gut-Skin Axis in Inflammatory Skin Diseases: What’s Gut got to do with Dermatology?
Jean McGee
1:30-2:00 pm
Pathogenic Mechanisms in Cutaneous Lupus
J. Michelle Kahlenberg
2:00-2:30 pm
An IgG-Macrophage Axis Suppresses IgE-Mediated Itch
Aron Gyorgypal
2:30-2:45 pm
Looking at the Memory Response and its Regulatory Mechanisms in Non-Lesional Skin of Vitiligo
Laure Migayron
2:45-3:00 pm
Friday, June 27, 2025
Resident Memory T Cells in Human Inflammatory Disease
Liv Eidsmo
8:00-8:30 am
Necroptosis and Resident Memory T cells in Fibrosing Disorders
Cris Crisler
8:30-9:00 am
Resident Memory T Cell Development is Gradual and Shows AP-1 Gene Expression in Mature Cells
Thomas Kupper
9:00-9:30 am
The Dirt on Dirty Mice: a Primer on Dirty Mice for Human Skin Investigators
Sherrie Divito
9:30-10:00 am
Break - Poster Session
10:00-10:30 am
Hidradenitis Suppurativa: New Insights
Johann Gudjonsson
10:30-11:00 am
Chronic Inflammation: Lessons Learned from CTCL
Patrick Brunner
11:00-11:30 am
Mouse Models of Psoriasis in 2025: Is there a Future?
Nicole Ward
11:30 am-12:00 pm
Lunch
12:00-1:00 pm
Skin Toxicities from Cancer Therapies: Insights into Diagnosis and Management
Nicole Leboeuf
1:00-1:30 pm
Morphea More Than Skin Deep. Morphea or Localized Scleroderma Affects Children and Adults
Heidi Jacobe
1:30-2:00 pm
Break - Poster Session
2:00-2:10 pm
Mitochondria: How our Cellular Powerhouses Affect Immunity, Tolerance and Responses to Injury
Rachael Clark
2:10-2:40 pm
Leveraging CTCL Mutations to Build Better CAR T cells
Jaehyuk Choi
2:40-3:10 pm
Closing Remarks and Poster Awards
Rachael Clark
3:10-3:25 pm
Faculty
Harvard Medical School Continuing Education attracts the best and brightest faculty from all around the world. As a student in this course, you’ll have access to outstanding course directors and faculty.

Rachael Clark, MD, PhD
Course Director
- Martin C. Mihm, Jr., MD and Shing-Yiu Yip Professorship in Dermatology, Harvard Medical School

William J. "Cris" Crisler, PhD
Course Director
- Instructor in Dermatology, Harvard Medical School

Jean McGee, MD, PhD, MS
Course Director
- Associate Professor of Dermatology, Harvard Medical School
Patrick Brunner, MD
Associate Professor of Dermatology, Icahn School of Medicine at Mount Sinai
Jaehyuk Choi, MD, PhD
Scheryle Simmons Patigian Distinguished Chair, Cancer Immunobiology
UT Southwestern Medical Center
Annemieke de Jong, PhD
Assistant Professor of Dermatology, Icahn School of Medicine at Mount Sinai
Sherrie Divito, MD, PhD
Assistant Professor of Dermatology, Harvard Medical School
Liv Eidsmo, MD, PhD
Professor of Dermatology and Venereology, Department of Medicine, Solna
Karolinska Institutet, Sweden
Richard Gallo, MD, PhD
Professor and Chair of Dermatology, University of California, San Diego
Michel Gilliet, MD
Professor and Chair of Dermatology, Centre Hospitalier Universitaire Vaudois, Switzerland
Elizabeth Grice, PhD
Sandra J. Lazarus Professor of Dermatology and Vice Chair of Research, University of Pennsylvania Perelman School of Medicine
Johann Gudjonsson, MD, PhD
Arthur C. Curtis Professor of Molecular Skin Immunology, University of Michigan
Heidi Jacobe, MD
Professor and Chair of Dermatology, University of Texas Southwestern Medical Center
J. Michelle Kahlenberg, MD, PhD
Professor of Internal Medicine and Dermatology; Giles Boles and Dorothy Mulkey Research Professor of Rheumatology, University of Michigan
Brian Kim, MD, MTR, FAAD
Sol and Clara Kest Professor and Vice Chair of Dermatology, Icahn School of Medicine at Mount Sinai
Thomas Kupper, MD
Thomas B. Fitzpatrick, Professor and Chair of Dermatology, Harvard Medical School
Nicole LeBoeuf, MD, MPH
Associate Professor and Vice Chair of Dermatology, Harvard Medical School
John O'Shea, MD
National Institute of Arthritis and Musculoskeletal and Skin Diseases Scientific Director; Chief, Molecular Immunology and Inflammation Branch, NIH/NIAMS
Jeffrey Smith, MD, PhD
Assistant Professor of Dermatology, Harvard Medical School/Brigham and Women’s Hospital
Erin Theisen, MD, PhD
Instructor in Dermatology, Harvard Medical School/Brigham and Women’s Hospital
Nicole Ward, PhD
Professor and Vice Chair of Dermatology, Vanderbilt University Medical Center
Location Information
Venue
Fairmont Copley Plaza
138 St. James Ave, Boston MA 02116
617-267-5300
Hotel Information can be found here.
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Course Fees
Fee Disclaimer
You may register through our secure online environment and will receive an email confirmation upon receipt of your payment. Prices include CME credit, an electronic syllabus, Refreshments, Breakfast, and Lunch.
At the end of the registration process, a $10 non-refundable processing fee will be added to your registration.
Review the cancellation policy.
All abstracts should be sent to skininflammation@bwh.harvard.edu
Role | Standard Price |
---|---|
Physician (MD/DO) | $750.00 |
PA | $350.00 |
Resident/Fellow | $350.00 |
Allied Health Professional / Other | $350.00 |