TOFA: A New Way to Lose Weight?
In this episode of Science Snapshot, learn how the oral compound TOFA helped obese mice lose weight by encouraging the body to burn more energy and fat—and how this approach differs from GLP-1-based medicines.
Most weight-loss therapies, including GLP-1-based medicines, work partly by helping people eat less. But a new study in obese mice has tested a different approach: an oral compound called TOFA that encourages the body to burn more energy and fat. The mice in the study lost weight without some of the side effects often seen with GLP-1-based medicines—but how does it work, and could it eventually be used in people? Watch the full video to find out.
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